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Index > Protein center > KLF10(Gene name) > Human
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  • KLF10 (Gene name),
  • Krueppel-like factor 10 (Protein name ),  KLF10_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    KLF10(TIEG;TIEG1);
    Protein name:
    Krueppel-like factor 10;
    Alternative:
    Transforming growth factor-beta-inducible early growth response protein 1(TGFB-inducible early growth response protein 1;TIEG-1);EGR-alpha;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    480
    Sequence:
    50:
    MLNFGASLQQ | TAEERMEMIS | ERPKESMYSW | NKTAEKSDFE | AVEALMSMSC | 
    100:
    SWKSDFKKYV | ENRPVTPVSD | LSEEENLLPG | TPDFHTIPAF | CLTPPYSPSD | 
    150:
    FEPSQVSNLM | APAPSTVHFK | SLSDTAKPHI | AAPFKEEEKS | PVSAPKLPKA | 
    200:
    QATSVIRHTA | DAQLCNHQTC | PMKAASILNY | QNNSFRRRTH | LNVEAARKNI | 
    250:
    PCAAVSPNRS | KCERNTVADV | DEKASAALYD | FSVPSSETVI | CRSQPAPVSP | 
    300:
    QQKSVLVSPP | AVSAGGVPPM | PVICQMVPLP | ANNPVVTTVV | PSTPPSQPPA | 
    350:
    VCPPVVFMGT | QVPKGAVMFV | VPQPVVQSSK | PPVVSPNGTR | LSPIAPAPGF | 
    400:
    SPSAAKVTPQ | IDSSRIRSHI | CSHPGCGKTY | FKSSHLKAHT | RTHTGEKPFS | 
    450:
    CSWKGCERRF | ARSDELSRHR | RTHTGEKKFA | CPMCDRRFMR | SDHLTKHARR | 
    480:
    HLSAKKLPNW | QMEVSKLNDI | ALPPTPAPTQ | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    String:
    UniGene:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Krueppel-like factor 10
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    E0688h
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    ELISA Kit for Human Krueppel-like factor 10
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    E0688m
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    ELISA Kit for Human Krueppel-like factor 10
    Cat.:
    E0688r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Krueppel-like factor 10
    Cat.:
    U0688m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Krueppel-like factor 10
    Cat.:
    U0688h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Krueppel-like factor 10
    Cat.:
    U0688r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Krueppel-like factor 10
    Cat.:
    P0688Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Krueppel-like factor 10
    Cat.:
    P0688Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Krueppel-like factor 10
    Cat.:
    P0688Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Krueppel-like factor 10
    Monoclonal Antibody for Human Krueppel-like factor 10
    Monoclonal Antibody for Human Krueppel-like factor 10
    Protein for Human Krueppel-like factor 10
    Protein for Human Krueppel-like factor 10
    Protein for Human Krueppel-like factor 10

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation."
      Blok L.J. , Grossmann M.E. , Perry J.E. , Tindall D.J.
      Mol. Endocrinol.9:1610-1620(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION
    2. 2.
      "Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts."
      Subramaniam M. , Harris S.A. , Oursler M.J. , Rasmussen K. , Riggs B.L. , Spelsberg T.C.
      Nucleic Acids Res.23:4907-4912(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INDUCTION
    3. 3.
      "TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters."
      Fautsch M.P. , Vrabel A. , Subramaniam M. , Hefferen T.E. , Spelsberg T.C. , Wieben E.D.
      Genomics51:408-416(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Shaking the family tree: Identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors."
      Camacho-Vanegas O. , Till J. , Miranda-Lorenzo I. , Ozturk B. , Camacho S.C. , Martignetti J.A.
      FASEB J.27:432-436(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4);ALTERNATIVE SPLICING
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Amygdala.
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Eye.
      tissue: Placenta.
    9. 10.
      "Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue."
      Johnsen S.A. , Subramaniam M. , Monroe D.G. , Janknecht R. , Spelsberg T.C.
      J. Biol. Chem.277:30754-30759(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SIAH1;UBIQUITINATION;PROTEASOMAL DEGRADATION
    10. 11.
      "Identification and characterization of a consensus DNA binding element for the zinc finger transcription factor TIEG/EGRalpha."
      Chrisman H.R. , Tindall D.J.
      DNA Cell Biol.22:187-199(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DNA-BINDING
    11. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-249;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 13.
      "Solution structure of the first and second ZF-C2H2 domains from human krueppel-like factor 10."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2008-04) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 353-423
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